Skip to main content
. 2021 Jan 18;9:e10718. doi: 10.7717/peerj.10718

Table 1. The published circRNAs with translation potential.

CircRNA source Research model Translation product Functions Reference
CircRNAs in viruses and bacteria Hepatitis δ virus Protein of 122 amino acids The hepatitis delta antigen (HDAg) Kos et al. (1986)
A virusoid associated with rice yellow mottle virus 16-kDa highly basic protein Unknown AbouHaidar et al. (2014)
Escherichia coli: 795-nt circular mRNA GFP Fluorescent Perriman & Ares Jr (1998)
HPV16-derived-circE7 E7 protein Influencing the development of cancer. Zhao et al. (2019)
Artificial circRNAs or synthetic modified RNA HEK-293 cells GFP Fluorescent Wang & Wang (2015)
Rabbit reticulocyte lysate and HeLa cells FLAG protein (EGF, IGF-1, IGF-2) Human growth factors Abe et al. (2015)
Rabbit reticulocyte lysate 23-kDa product Unknown Chen & Sarnow (1995)
HEK293 cells GFP, Firefly luciferase, human erythropoietin Convenient for the author to test Wesselhoeft, Kowalski & Anderson (2018)
Endogenous circRNAs Drosophila: circMbl3 37.04-kDa protein Unknown Pamudurti et al. (2017)
Human: circ-ZNF609 circ-ZNF609-encoded protein Unknown Legnini et al.(2017)
Human: circ-FBXW7 FBXW7-185aa Cooperates with FBXW7 to control c-Myc stability Yang et al. (2018)
Human: circ-SHPRH SHPRH-146aa Guarding against full-length SHPRH protein degradation Zhang et al. (2018a)
Human: CircPINTexon2 PINT87aa Inhibiting oncogenes transcriptional elongation Zhang et al. (2018b)
Human: circPPP1R12A circPPP1R12A-73aa Promoting the colon cancer pathogenesis and metastasis Zheng et al. (2019)
Human: circβ-catenin β-catenin-370aa Stabilizing full-length β-catenin Liang et al. (2019)
Drosophila: circSfl circlSfl protein Extending the lifespan of fruit flies Weigelt et al. (2020)