Table 5.
Up-regulated detoxification enzymes in the Met-R strain
| Gene family | Unigene ID | Phylogenetic classification | Best Uniref50 match | BLAST-based annotation | Expert annotationa | log2FC | FDR |
|---|---|---|---|---|---|---|---|
| P450 | DN26728_c0_g1 | Clan 3 | M4W605 | CYP6BQ8 | CYP6BQ11 | 3.56 | 8.9e-12 |
| DN29475_c1_g7 | Clan 4 | A0A0T6B959 | – | CYP3747A | 2.12 | 1.6e-04 | |
| DN28703_c3_g1 | Clan 3 | A0A0T6BCU6 | – | CYP6RU | 1.96 | 2.3e-04 | |
| DN23343_c0_g1 | Clan 3 | V5GHG9 | CYP6A1 | CYP6RU | 1.96 | 1.5e-03 | |
| DN28703_c3_g3 | Clan 3 | D7EJA5 | CYP6BK4 | CYP6RU1 | 1.62 | 1.6e-03 | |
| DN26679_c1_g1 | Clan 4 | N6URV7 | CYP349B1 | CYP3747A | 1.44 | 3.6e-02 | |
| UGT | DN28972_c1_g2 | N/A | A0A1Y1JU93 | UGT | N/A | 3.87 | 2.3e-02 |
aExpert manual annotation was kindly provided by Dr. David Nelson