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. 2021 Jan 21;21:32. doi: 10.1186/s12876-021-01609-8

Table 2.

Relative risk of micro-nutrient deficiency

Variable Uni-variate analysis Multi-variate analysis
OR (95% CI) P-value Adjusted OR (95% CI) P-value
Male sex 0.842 (0.478–1.485) 0.553 0.718 (0.375–1.376) 0.319
Age 0.975 (0.958–0.993) 0.006 0.973 (0.949–0.998) 0.037
The path of laboratory test
 Outpatients clinic 1.0 (Ref.) 1.0 (Ref.)
 Hospitalization patients 2.204 (0.735–6.608) 0.158 2.459 (0.715–8.461) 0.154
Type of disease
 UC 1.0 (Ref.) 1.0 (Ref.)
 CD 3.810 (1.721–8.430) 0.001 2.492 (1.012–6.136) 0.047
 Intestinal BD 2.778 (0.734–10.513) 0.132 1.356 (0.284–6.479) 0.703
Medications
 5-ASA 0.381 (0.214–0.679) 0.001 0.548 (0.281–1.068) 0.077
 Steroids 0.502 (0.132–1.914) 0.313
 Azathioprine 1.784 (0.983–3.238) 0.057
 Anti-TNF 1.584 (0.900–2.788) 0.111
 Methotrexate 0.746 (0.340–1.637) 0.465
 Othersa 0.295 (0.063–1.383) 0.121
Operation 2.041 (1.120–3.717) 0.020 2.714 (1.260–5.844) 0.011
Underlying disease
 Hypertension 0.515 (0.053–5.037) 0.568
 Osteoporosis 0.776 (0.371–1.624) 0.501 1.500 (0.699–3.217) 0.298
 Othersb 1.131 (0.579–2.206) 0.719 2.459 (0.715–8.461) 0.154

OR, odds ratio; CI, confidence interval; UC, Ulcerative colitis; CD, Crohn’s disease; BD, Behçet’s disease; 5-ASA, 5-aminosalicylic acid; anti-TNF, anti-tumor necrosis factor

aMongersen, vedolizumab

bMDS, SLE, AR, BOOP, OA, Osteoporosis, CAOD, cancer