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. 2021 Jan 21;21:39. doi: 10.1186/s12906-021-03207-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Hind paws swelling in Wistar rats at 0, 6, 12, 15, 19, and 25 days after AIA initiation. Data are shown as median with IQR. a-f Hind paws swelling measurements, * denotes statistically significant differences Control– vs group - *(p < 0.05), **(p < 0.01), ***(p < 0.001), while Δ(p < 0.05) denotes statistically significant differences compared to MIC group, and $(p < 0.05) denotes statistically significant differences compared to LIPO group. g Pictures of swelled hind paws 15 and 25 days after CFA injection. All treatment period (see Additional file 6)