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. 2019 Dec 26;1:11. doi: 10.1186/s42238-019-0011-z

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Relationships of major cannabinoids. Cannabidiol acid (CBDA) and Tetrahydrocannabinol acid (THCA) are synthesized from Cannabigerolic acid (CBGA) by enzymatic reaction. These acidic molecules are changed to the more commonly known forms by decarboxylation, usually by applying heat