Table 2.

THC pharmacokinetic parameters after inhalation

	Group I 10 ± 0.1 mg	Group II 15 ± 0.1 mg	Group III 20 ± 0.1 mg	Group IV 25 ± 0.1 mg
Δ9-THC Cmax (ng/mL)	35.43 ± 5.97	51.47 ± 13.79	72.37 ± 15.93	88.63 ± 14.75
AUC0-∞ (ng min/mL)	441.59 ± 88.49	624 ± 123.56	698.35 ± 174.98	971.36 ± 310.4
Tmax (min)	3.666 ± 0.471	3.333 ± 0.471	2.666 ± 0.942	3 ± 0.816

Each THC dosage group concise of four healthy volunteers. Both Δ⁹-THC C_max and AUC_0-∞ measured in plasma of the volunteers and calculated from the same data, are showing a linear increase in mean maximum plasma concentration of THC (C_max) and area under the curve (AUC) both with no change in the time needed to reach such concentration

THC C_max Tetrahydrocannabinol maximum concentration, AUC Area under the curve, T_max time to reach maximum concentration