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. 2021 Jan 21;17(1):e1009151. doi: 10.1371/journal.ppat.1009151

Fig 1. G protein-coupled receptors in Caenorhabditis elegans regulate innate immunity in the worm.

Fig 1

(A) A lateral view of the head region, representing the neurons expressing the immunomodulatory GPCRs, NPR-1, NPR-8, NPR-9, OLRN-1, DOP-4, and OCTR-1. (B) A lateral view of the posterior end representing the regions/cells expressing the immunomodulatory GPCRs, FSHR-1, DCAR-1, PCDR-1, and NPR-1. (C) A schematic overview of GPCRs regulating various immune response components in C. elegans. AMP, antimicrobial peptides; DAMP, damage-associated molecular pattern; GPCR, G protein-coupled receptor; HPLA, 4-hydroxyphenyllactic acid; UPR, unfolded protein response.