Table 2.

Binding affinities of the 15 molecules used in flexible docking studies (kcal/mol)

	BRD2			MPro
	Lowest	Mean	SEM	Lowest	Mean	SEM
3-PROPYLIDENE PHTHALIDE	−6.7	− 6.63	0.07	− 7.0	− 6.83	0.09
BENZYL BENZOATE	−8.1	−7.95	0.10	−6.3	−5.83	0.17
BENZYL CINNAMATE	−8.3	−8.30	0.00	−6.8	−6.65	0.07
BENZYL SALICYLATE	−8.1	−7.88	0.09	−6.9	−6.70	0.07
BETA CARYOPHYLLENE	−7.4	− 7.40	0.00	−5.4	− 5.33	0.03
DIHYDROAMBRETTOLIDE	−8.0	− 7.83	0.17	−7.1	−6.97	0.09
GALAXOLIDE	−8.6	− 8.40	0.10	−7.4	−7.37	0.03
LYRAL	−6.8	− 6.63	0.06	−6.7	−5.58	0.39
SCLAREOL	−7.5	− 7.37	0.07	−8.0	−7.73	0.15
VERTOFIX (ALPHA ACETYL CEDRENE)	−6.9	−6.77	0.09	−7.2	−7.00	0.12
Artemisinin	−7.9	−7.75	0.09	−7.4	− 7.15	0.13
Favipiravir	−6.0	−5.75	0.22	−6.0	− 5.50	0.30
Hydroxychloroquine	−7.1	−6.85	0.10	−6.6	−6.30	0.12
Nigellidine	−8.8	−8.50	0.18	− 8.3	−7.83	0.21
Remdesivir	−8.9	−8.50	0.16	−8.4	− 8.10	0.18