Table.
Baseline Characteristics
| Total (n=9) | HF hospitalization within 1 year | P-value | ||
|---|---|---|---|---|
| Yes (n=3) | No (n=6) | |||
| Age (years) | 78 [74, 82] | 78 [77, 81] | 78 [68, 85.3] | 1.000 |
| Male sex | 8 (89) | 2 (67) | 6 (100) | 0.330 |
| Wild-type TAC | 8 (89) | 2 (67) | 6 (100) | 0.330 |
| Body surface area (m2) | 1.6 [1.5, 1.74] | 1.5 [1.3, 1.5] | 1.7 [1.6. 1.8] | 0.020 |
| Body mass index (kg/m2) | 21.0 [20.0, 23.7] | 19.0 [18.2, 21.4] | 22.4 [20.5, 24.4] | 0.121 |
| NYHA functional class | 0.021 | |||
| Class I | 0 (0) | 0 (0) | 0 (0) | |
| Class II | 5 (56) | 0 (0) | 5 (83) | |
| Class III | 3 (33) | 2 (66) | 1 (17) | |
| Class IV | 1 (11) | 1 (33) | 0 (0) | |
| No. previous HF hospitalizations | 1 [1, 3] | 3 [1, 4] | 1 [1, 1.75] | 0.217 |
| Duration of HF (months) | 32 [12, 50] | 60 [44, 60] | 16 [5.8, 37] | 0.038 |
| Atrial fibrillation (%) | 4 (33) | 1 (33) | 3 (50) | 1.000 |
| Cardiac pacemaker (%) | 4 (44) | 2 (67) | 2 (33) | 0.524 |
| Troponin I (ng/mL) | 95 [78, 251] | 251 [89, 660] | 86 [66, 508] | 0.302 |
| Plasma BNP (pg/mL) | 289 [213, 618] | 735 [349, 1,405] | 215 [165, 462] | 0.053 |
| Serum NT-proBNP (pg/mL) | 3,053 [1,286, 3,368] | 7,779 [6,155, 9,403] | 3,085 [1,501, 4,729] | 0.064 |
| Serum creatinine (mg/dL) | 1.25 [0.94, 1.43] | 1.73 [0.94, 1.77] | 1.19 [0.9, 1.37] | 0.197 |
| LVEF (%) | 55 [48, 57] | 55 [15, 57] | 54 [32, 62] | 0.606 |
| IVST (mm) | 15 [14, 17] | 17 [15, 18] | 13.5 [12, 15.3] | 0.051 |
| LV SV (mL) | 43 [36, 50] | 36.0 [16.1, 58.0] | 44.0 [39.8, 56.8] | 0.439 |
| LV SVI (mL/m2) | 28.9 [27.3, 29.3] | 27.3 [10.7, 29.4] | 29.0 [25.7, 32.7] | 0.439 |
Unless indicated otherwise, data are given as the median [interquartile range] or n (%). *P<0.05 by Mann-Whitney U-test or Fisher’s exact test as appropriate. BNP, B-type natriuretic peptide; HF, heart failure; IVST, interventricular septum thickness; LV, left ventricular; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro B-type natriuretic peptide; NYHA, New York Heart Association; SV, stroke volume; SVI, stroke volume index; TAC, transthyretin amyloid cardiomyopathy.