Table 2.
Participant | Specimen | Race/ethnicity | Age | Source | Stage/histologya | Prior treatment | Days from last infusion |
---|---|---|---|---|---|---|---|
1 | OV469 | White/non-Hispanic | 56 | Ascites | IIIC HGS Peritoneal cancer |
Untreated | NA |
2 | OV778 | White/non-Hispanic | 74 | Ascites | IVB HGSOC | Untreated | NA |
3b | OV798 OV817 OV820 OV838 OV840 |
White/non-Hispanic | 61 | Pleural effusion | IIIC HGSOC | C1 paclitaxel/bevacizumab C4 paclitaxel/bevacizumab C5 paclitaxel/bevacizumab C6 paclitaxel/bevacizumab C1 gemcitabine |
21 14 7 14 2 |
4 | OV899 OV860 |
White/non-Hispanic | 74 | Ascites | IIIC HGSOC | Untreated C1 carboplatin/paclitaxel |
NA 4 |
5 | OV867 OV875 OV882 |
White/non-Hispanic | 62 | Ascites Ascites Ascites |
IVB HGSOC | C1 carboplatin/paclitaxel C1 carboplatin/doxorubicin C1 carboplatin/doxorubicin |
3 |
6c | OV870 OV888 |
White/non-Hispanic | 54 | Ascites Ascites |
IIIC HGSOC | See footnote | 46 |
C = Cycle; HGS = High grade serous; HGSOC = High grade serous ovarian cancer.
Stage at time of original diagnosis.
Prior to first specimen, patient underwent treatment with AZD2014, bevacizumab, carboplatin, cisplatin, doxorubicin, olaparib, paclitaxel, topotecan, in combination or as a single agent.
Prior to first specimen, patient underwent treatment with ABT888 (PARP inhibitor), bevacizumab, carboplatin, pegylated liposomal doxorubicin, paclitaxel, topotecan. Prior to collection of OV888, patient initiated therapy with anastrazole.