Table 1.
Baseline characteristics
| Patients (n = 46) | % | |
|---|---|---|
| Age (years; median, range) | 58 (29–68) | |
| Sex | ||
| Male | 26 | 57 |
| Female | 20 | 43 |
| ECOG PS | ||
| 0 | 35 | 76 |
| 1 | 11 | 24 |
| Site of primary tumor | ||
| Right colon | 10 | 22 |
| Left colon | 16 | 35 |
| Rectum | 20 | 43 |
| Resection of primary tumor | ||
| Yes | 17 | 37 |
| No | 29 | 63 |
| Site of metastases* | ||
| Liver | 36 | 78 |
| Lung | 13 | 28 |
| Lymph node | 7 | 15 |
| Peritoneum | 4 | 9 |
| UGT1A1 | ||
| Wild type (*1/*1) | 24 | 52 |
| Single heterozygous (*1/*6 or *1/*28) | 22 | 48 |
| RAS | ||
| Wild type | 17 | 37 |
| Mutated | 24 | 52 |
| Unknown | 5 | 11 |
ECOG PS Eastern Cooperative Oncology Group performance status, Right colon cecum, ascending and transverse colon, Left colon descending and sigmoid colon
*Site of metastases were counted in duplicate