Table 4.
Summary of selected data with laser monotherapy compared with non-surgical mechanical instrumentation alone
| Article (year) | Mean PPD change | Residual PPD | Mean CAL change | Mean BoP/BI change | Mean PI/PLI change | Mean changes in subgingival biofilm composition | Mean changes in GCF biomarker levels | PROMS |
|---|---|---|---|---|---|---|---|---|
| Schwarz (2001 and 2003) | +,+* | +,+* | +,+* | +,+* | − | − | NR | NR |
| Sculean (2004) | − | NR | − | − | − | NR | NR | NR |
| Crespi (2007) | +* | +* | +* | − | − | NR | NR | NR |
| Kamma (2009) | − | − | − | − | − | NR | NR | NR |
| Rotundo (2010) | − | − | − | − | − | NR | NR | − |
| Wang (2017) | − | +1 | − | − | − | + | − | NR |
| Grezch (2018) | − | - | +1 | + | + | + | NR | NR |
| Total (statistically significant) | 2 | 3 | 3 | 2 | 1 | 4 | 0 | 0 |
1For shallow sites (1–3 mm); 2for moderately deep sites (4–6 mm); 3for deep sites (> 7 mm); +statistically significant, −statistically not significant, *1-year outcome; 2-year outcomes, NR not reported, NA not applicable