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. 2021 Jan 21;11:1873. doi: 10.1038/s41598-021-81518-8

Table 2.

Comparison of the sensitivity and time to detection for MCDA and LAMP targeting ORF1ab from 3 independent runs.

DNA copies per reaction MCDA average detection time (min) MCDA reps$ LAMP average detection time (min) LAMP reps$
10 55.3 1/9 17.1 ± 6.3 3/9
25 46.4 ± 15 3/9 11.8 ± 0.5 5/9
50 20.2 ± 9 8/9 12.2 ± 2.1* 9/9*
100 13.6 ± 3.9 6/9 10.4 ± 0.8 8/9
500 12.6 ± 1.3* 9/9* 9.7 ± 0.2 9/9
1000 11.2 ± 0.3 9/9 9.5 ± 0.1 9/9
10,000 9.7 ± 0.3 9/9 8.4 ± 0.1 9/9

*Limit of detection.

$reps: 3 runs with 3 technical replicates = 9 replicates.