Table 2.

Demographics for the study population.

Variable	HCs	A	R	p value
n	16	15	10
Age, mean (SD)	40.8(13.9)	33.8(14.8)	30.5(11.9)	0.136
Male, %	56.3%	73.3%	60%	0.270
Serum NfL median (IQR) pg/ml	7.70 (6.13–9.78)	146.73 (120.91–411.31)	40.31 (19.54–151.05)	< 0.001

HCs healthy controls, A patients with MELAS in the acute attack, R patients with MELAS in the remission phase, NfL neurofilament light.