Table 1.
Serum metabolites with significant differences between patients with and without MHE.
| ID Biocrates | logFCa | FDRb | ID Biocrates | logFCa | FDRb |
|---|---|---|---|---|---|
| PC aa C36:4 | − 0.7436 | 0.0005 | PC aa C38:5 | − 0.6788 | 0.0009 |
| PC aa C38:4 | − 0.7106 | 0.0006 | PC aa C38:3 | − 0.5105 | 0.0165 |
| PC aa C38:5 | − 0.6788 | 0.0009 | alpha-AAA | − 0.4547 | 0.0167 |
| PC aa C40:5 | − 0.6272 | 0.0015 | PC aa C40:4 | − 0.4155 | 0.0228 |
| PC aa C34:4 | − 0.8185 | 0.0038 | PC aa C36:6 | − 0.6148 | 0.0230 |
| lysoPC a C20:4 | − 0.5669 | 0.0041 | lysoPC a C20:3 | − 0.6249 | 0.0245 |
| PC aa C40:6 | − 0.7801 | 0.0046 | PC aa C34:3 | − 0.5725 | 0.0250 |
| PC aa C38:6 | − 0.8598 | 0.0051 | Val | − 0.4825 | 0.0296 |
| PC ae C38:0 | − 0.5767 | 0.0055 | SM C22:3 | 1.1125 | 0.0372 |
| Met | 0.6004 | 0.0063 | PC aa C32:3 | − 0.3489 | 0.0379 |
| PC aa C36:5 | − 0.8773 | 0.0067 | PC aa C42:1 | 0.3616 | 0.0386 |
| SM (OH) C14:1 | 0.5611 | 0.0075 | SM C16:0 | 0.3501 | 0.0399 |
| PC ae C44:6 | 0.6000 | 0.0137 | PC ae C30:0 | 0.4426 | 0.0409 |
| Spermine | − 0.3971 | 0.0139 | PC ae C42:5 | 0.5168 | 0.0424 |
| PC aa C36:4 | − 0.7436 | 0.0005 | PC ae C44:5 | 0.5536 | 0.0473 |
| PC aa C38:4 | − 0.7106 | 0.0006 | C18:2 | 0.4845 | 0.0477 |
Lipids are described with the notation “Cx:y”, where x denotes the number of carbons in the side chain and y denotes the number of double bonds.
PC phosphatidylcholine, lysoPC lysophosphatidylcholine, SM sphingomyelin. alogFC: log2-fold-change; bp-value of t-test calculated and adjusted by FDR with the limma R package.