Table 2.
Estimated incidence of first psychiatric diagnoses during the first 14 to 90 days after a diagnosis of COVID-19 compared with other health events
COVID-19 |
Influenza in matched cohort (n=26 497) |
Other respiratory tract infection in matched cohort (n=44 775) |
Skin infection in matched cohort (n=38 977) |
Cholelithiasis in matched cohort (n=19 733) |
Urolithiasis in matched cohort (n=28 827) |
Fracture in matched cohort (n=37 841) |
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% (95% CI) | % (95% CI) | p value | % (95% CI) | p value | % (95% CI) | p value | % (95% CI) | p value | % (95% CI) | p value | % (95% CI) | p value | ||
Psychiatric illness | 5·8 (5·2–6·4) | 2·8 (2·5–3·1) | <0·0001 | 3·4 (3·1–3·7) | <0·0001 | 3·3 (3–3·7) | <0·0001 | 3·2 (2·8–3·7) | <0·0001 | 2·5 (2·2–2·8) | <0·0001 | 2·5 (2·2–2·7) | <0·0001 | |
Psychotic disorder | 0·1 (0·08–0·2) | 0·04 (0·01–0·10) | 0·019 | 0·1 (0·06–0·16) | 0·23 | 0·15 (0·096–0·24) | 0·83 | 0·11 (0·054–0·24) | 0·21 | 0·044 (0·016–0·12) | 0·0051 | 0·16 (0·11–0·24) | 0·77 | |
Mood disorder | 2·0 (1·7–2·4) | 1·1 (0·9–1·3) | <0·0001 | 1·5 (1·3–1·7) | 0·0054 | 1·7 (1·5–1·9) | 0·55 | 1·6 (1·3–1·9) | 0·14 | 1·2 (1–1·4) | 0·00011 | 1·4 (1·2–1·6) | 0·0050 | |
Anxiety disorder | 4·7 (4·2–5·3) | 2·2 (1·9–2·5) | <0·0001 | 2·5 (2·2–2·8) | <0·0001 | 2·4 (2·1–2·7) | <0·0001 | 2·6 (2·2–3) | <0·0001 | 1·8 (1·6–2·1) | <0·0001 | 1·6 (1·4–1·8) | <0·0001 | |
Insomnia | 1·9 (1·6–2·2) | 0·6 (0·5–0·8) | <0·0001 | 0·8 (0·7–1·0) | <0·0001 | 0·89 (0·73–1·1) | <0·0001 | 1·1 (0·88–1·4) | <0·0001 | 0·57 (0·43–0·74) | <0·0001 | 0·7 (0·57–0·85) | <0·0001 | |
Dementia in all participants | 0·44 (0·33–0·60) | 0·11 (0·06–0·20) | 0·00044 | 0·25 (0·18–0·35) | 0·00063 | 0·28 (0·20–0·39) | 0·13 | 0·24 (0·14–0·38) | <0·0001 | 0·16 (0·09–0·28) | <0·0001 | 0·34 (0·25–0·44) | 0·14 | |
Dementia (among those ≥65 years) | 1·6 (1·2–2·1) | 0·66 (0·41–1·1) | 0·0043 | 0·84 (0·61–1·1) | 0·00071 | 0·70 (0·49–1·0) | 0·00069 | 0·58 (0·36–0·94) | <0·0001 | 0·60 (0·38–0·95) | <0·0001 | 0·94 (0·68–1·3) | 0·0036 |
p values obtained using a log-rank test. A breakdown of the results for different diagnoses of the anxiety disorders and mood disorders categories is provided in the appendix (pp 26–27).