Figure 6.

Serum levels of LBP, zonulin and I-FABP in MDD patients and absolute number of circulating Tregs and their CD25^hiFoxP3⁺ and CD25^lowFoxP3⁺ subsets in high-LBP and normal-LBP MDD patients. Serum concentrations (y axis) of LBP (ng/ml), zonulin (mg/ml) and I-FABP (pg/ml) in MDD patients (gray box plots) and healthy controls (white box plots) (A). Absolute number of circulating Tregs and their CD25^hiFoxP3⁺ and CD25^lowFoxP3⁺ subsets (y axis) in high-LBP (ascending lined box plots) and normal-LBP (descending lined box plots) MDD patients subsets and healthy controls (white box plots) (B). The top of the rectangle indicates the third quartile, the horizontal line near the middle of the rectangle indicates the median, and the bottom of the rectangle indicates the first quartile. A vertical line extends from the top of the rectangle to indicate the maximum value, and another vertical line extends from the bottom of the rectangle to indicate the minimum value. *Significant difference between MDD and healthy controls for the indicated variable.