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. 2021 Jan 8;7:594600. doi: 10.3389/fvets.2020.594600

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Copyright © 2021 Tillis, Iredale, Childress, Graham, Wellehan, Isaza and Ossiboff.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Photomicrographs of granulomatous inflammation of the hemipenes and cloaca. Large, well-demarcated granulomas expand and compress the submucosa and mucosa of the hemipenes; hematoxylin and eosin, 20× magnification (A). Granulomas surround cores of cellular debris, acicular (cholesterol) clefts, mineral, and mixed morphology bacteria; hematoxylin and eosin, 100× magnification (B). A consistent subpopulation of filamentous, Gram-positive bacteria are present throughout the granulomas, and at the highest concentration of the margins of the granulomas with extension into the wall of the granuloma, Gram, 600× magnification (C).