. 2021 Jan 21;11:2015. doi: 10.1038/s41598-021-81770-y

Table 1.

Changes in RVD in the superficial and deep layers of myopic and emmetropic eyes before exercise, after 20 min of exercise, and after 30 min of rest.

	Variables	Pre-exercise (95% CI)	Post-exercise (95% CI)	Rest (95% CI)	P Value (post–pre/rest-pre)
Myopia (N = 40)	Superficial overall RVD(%)	43.35 ± 1.63 (42.83–43.87)	43.25 ± 1.50 (42.77–43.73)	43.63 ± 1.45 (43.17–44.09)	0.462/0.061
Superficial parafoveal RVD (%)	48.88 ± 1.57 (48.37–49.38)	48.82 ± 1.53 (48.33–49.31)	49.20 ± 1.50 (48.72–49.68)	0.668/0.030
Superficial foveal RVD (%)	21.24 ± 4.99 (19.65–22.84)	20.97 ± 5.05 (19.35–22.58)	21.35 ± 5.00 (19.75–22.95)	0.405/0.744
Deep overall RVD (%)	44.20 ± 1.41 (43.80–44.68)	43.87 ± 1.55 (43.52–44.51)	44.28 ± 1.52 (43.88–44.76)	0.022/0.568
Deep parafoveal RVD (%)	50.90 ± 1.71 (50.42–51.59)	50.54 ± 1.75 (50.01–51.32)	51.03 ± 1.68 (50.58–51.58)	0.031/0.517
Deep foveal RVD (%)	17.37 ± 4.59 (15.91–19.00)	17.19 ± 4.21 (16.12–18.59)	17.30 ± 4.30 (15.92–18.92)	0.619/0.865
Control (N = 18)	Superficial overall RVD(%)	41.66 ± 1.19 (41.07–42.25)	41.78 ± 1.27 (41.15–42.42)	42.19 ± 1.34 (41.53–42.86)	0.399/0.008
Superficial parafoveal RVD (%)	47.04 ± 1.32 (46.38–47.70)	46.19 ± 1.77 (45.31–47.07)	47.56 ± 1.44 (46.84–48.27)	0.129/0.015
Superficial foveal RVD (%)	20.14 ± 3.87 (18.21–22.06)	20.72 ± 4.17 (18.64–22.79)	20.73 ± 4.22 (18.64–22.83)	0.036/0.036
Deep overall RVD (%)	42.19 ± 1.63 (41.38–43.00)	42.67 ± 2.01 (41.67–43.67)	43.08 ± 1.73 (42.22–43.95)	0.054/0.002
Deep parafoveal RVD (%)	48.84 ± 1.59 (48.05–49.63)	49.38 ± 2.06 (48.36–50.41)	49.96 ± 1.81 (49.06–50.86)	0.072/0.003
Deep foveal RVD (%)	15.56 ± 3.72 (13.71–17.41)	15.80 ± 3.71 (13.96–17.65)	15.57 ± 4.35 (13.41–17.74)	0.125/0.977

Variables

Pre-exercise
(95% CI)

Post-exercise
(95% CI)

Rest
(95% CI)

P Value
(post–pre/rest-pre)

Myopia

(N = 40)

Superficial overall RVD(%)

43.35 ± 1.63

(42.83–43.87)

43.25 ± 1.50

(42.77–43.73)

43.63 ± 1.45

(43.17–44.09)

0.462/0.061

Superficial parafoveal RVD (%)

48.88 ± 1.57

(48.37–49.38)

48.82 ± 1.53

(48.33–49.31)

49.20 ± 1.50

(48.72–49.68)

0.668/0.030

Superficial foveal RVD (%)

21.24 ± 4.99

(19.65–22.84)

20.97 ± 5.05

(19.35–22.58)

21.35 ± 5.00

(19.75–22.95)

0.405/0.744

Deep overall RVD (%)

44.20 ± 1.41

(43.80–44.68)

43.87 ± 1.55

(43.52–44.51)

44.28 ± 1.52

(43.88–44.76)

0.022/0.568

Deep parafoveal RVD (%)

50.90 ± 1.71

(50.42–51.59)

50.54 ± 1.75

(50.01–51.32)

51.03 ± 1.68

(50.58–51.58)

0.031/0.517

Deep foveal RVD (%)

17.37 ± 4.59

(15.91–19.00)

17.19 ± 4.21

(16.12–18.59)

17.30 ± 4.30

(15.92–18.92)

0.619/0.865

Control

(N = 18)

Superficial overall RVD(%)

41.66 ± 1.19

(41.07–42.25)

41.78 ± 1.27

(41.15–42.42)

42.19 ± 1.34

(41.53–42.86)

0.399/0.008

Superficial parafoveal RVD (%)

47.04 ± 1.32

(46.38–47.70)

46.19 ± 1.77

(45.31–47.07)

47.56 ± 1.44

(46.84–48.27)

0.129/0.015

Superficial foveal RVD (%)

20.14 ± 3.87

(18.21–22.06)

20.72 ± 4.17

(18.64–22.79)

20.73 ± 4.22

(18.64–22.83)

0.036/0.036

Deep overall RVD (%)

42.19 ± 1.63

(41.38–43.00)

42.67 ± 2.01

(41.67–43.67)

43.08 ± 1.73

(42.22–43.95)

0.054/0.002

Deep parafoveal RVD (%)

48.84 ± 1.59

(48.05–49.63)

49.38 ± 2.06

(48.36–50.41)

49.96 ± 1.81

(49.06–50.86)

0.072/0.003

Deep foveal RVD (%)

15.56 ± 3.72

(13.71–17.41)

15.80 ± 3.71

(13.96–17.65)

15.57 ± 4.35

(13.41–17.74)

0.125/0.977

RVD retinal vessel density, CI confidence interval, post–pre comparisons by paired t tests for post-exercise vs. pre-exercise, rest-pre: comparisons by paired t tests for post-rest vs. pre-exercise.

Bold values indicate statistical significance: p < 0.05.