Table 1.

Protein–protein interaction depicting 5 lowest binding energy for S Protein–ACE2 complex in the presence or absence of curcumin and catechin.

Macromolecule	Binding positions	Lowest energy (kJ/mol)	Average lowest energy (kJ/mol)
S Protein–ACE2	1	− 928.9	− 901.2
S Protein–ACE2	2	− 923
S Protein–ACE2	3	− 902.4
S Protein–ACE2	4	− 853.3
S Protein–ACE2	5	− 898.4
S Protein with curcumin–ACE2	1	− 799.2	− 759.54
S Protein with curcumin–ACE2	2	− 744
S Protein with curcumin–ACE2	3	− 759
S Protein with curcumin–ACE2	4	− 755
S Protein with curcumin–ACE2	5	− 740.5
S Protein with catechin–ACE2	1	− 799.2	− 759.54
S Protein with catechin–ACE2	2	− 744
S Protein with catechin–ACE2	3	− 759
S Protein with catechin–ACE2	4	− 755
S Protein with catechin–ACE2	5	− 740.5