Table 3.
Tumor subtypes of CBCS patientsa.
| Gene | Basal-like | Luminal A | Luminal B | HER2 + ER− | All negative | Total |
|---|---|---|---|---|---|---|
| BRCA1 | 6 (0.038) | 5 (0.011) | 2 (0.024) | 0 (0.000) | 3 (0.029) | 16 (0.018) |
| BRCA2 | 5 (0.032) | 12 (0.025) | 4 (0.048) | 0 (0.000) | 5 (0.048) | 26 (0.030) |
| PALB2 | 3 (0.019) | 5 (0.011) | 1 (0.012) | 0 (0.000) | 0 (0.000) | 9 (0.010) |
| CHEK2 | 0 (0.000) | 9 (0.019) | 2 (0.024) | 0 (0.000) | 0 (0.000) | 11 (0.013) |
| ATM | 2 (0.013) | 2 (0.004) | 2 (0.024) | 0 (0.000) | 1 (0.010) | 7 (0.008) |
| Other gene | 5 (0.032) | 21 (0.044) | 2 (0.024) | 2 (0.039) | 3 (0.029) | 33 (0.038) |
| No mutation | 136 (0.872) | 425 (0.895) | 71 (0.845) | 49 (0.961) | 94 (0.895) | 775 (0.890) |
| Total | 156 (1.000) | 475 (1.000) | 84 (1.000) | 51 (1.000) | 105 (1.000) | 871 (1.000) |
aIn parentheses, proportions of tumors of each subtype with mutation.