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. 2021 Jan 21;11:2007. doi: 10.1038/s41598-021-81604-x

Figure 4.

Figure 4

Sensitivity and time-dependent cumulative analyses. (A) Sensitivity analysis by sequential omission of every study. Each line refers to the global odds ratio (OR) after excluding the corresponding study. In all cases, the OR is statistically significantly in favor of a risk of developing acute myeloid leukemia (AML) related to occupational pesticide exposure (OPE). (B) Time-dependent analyses after adding each study down to the full 14 publications. The OR, in favor of AML risk related to OPE, becomes statistically significant after the cumulative inclusion of 2,689 patients (from Wong O et al.). This figure was performed using R software30 with the “metafor” package28.