Table 2.

Adjusted hazard ratios, 95% confidence intervals, and incidence rates of end-stage renal disease development according to the presence of each MetS component.

	N	Events (n)	Follow-up duration (person-years)	Incidence rate (per 1000 person-years)	Adjusted hazard ratios ( 95% confidence intervals)
					Model 1	Model 2	Model 3
WC criterion
No	10,544,298	12,275	52,652,426	0.23	1 (ref.)	1 (ref.)	1 (ref.)
Yes	2,766,626	6,307	13,733,667	0.46	1.45 (1.41, 1.49)	1.51 (1.45, 1.57)	1.55 (1.49, 1.61)
BP criterion
No	7,181,413	2,252	35,937,081	0.06	1 (ref.)	1 (ref.)	1 (ref.)
Yes	6,129,511	16,330	30,449,013	0.54	4.85 (4.63, 5.07)	5.23 (5.00, 5.48)	4.57 (4.36, 4.78)
Glucose criterion
No	8,904,300	6,473	44,579,195	0.15	1 (ref.)	1 (ref.)	1 (ref.)
Yes	4,406,624	12,109	21,806,898	0.56	2.53 (2.46, 2.61)	2.59 (2.51, 2.67)	2.26(2.19, 2.33)
TG criterion
No	8,303,071	6,610	41,430,791	0.16	1 (ref.)	1 (ref.)	1 (ref.)
Yes	5,007,853	11,972	24,955,302	0.48	2.25 (2.19, 2.32)	2.29 (2.22, 2.36)	2.1 (2.03,2.16)
HDL-C criterion
No	9,204,479	6662	46,048,303	0.15	1 (ref.)	1 (ref.)	1 (ref.)
Yes	4,106,445	11,920	20,337,791	0.59	3.11 (3.01, 3.20)	2.99 (2.90, 3.09)	2.66 (2.58, 2.75)
MetS
No	9,272,955	5498	46,399,629	0.12	1 (ref.)	1 (ref.)	1 (ref.)
Yes	4,037,969	13,084	19,986,465	0.65	3.51 (3.40, 3.63)	4.07 (3.93, 4.22)	3.57 (3.45, 3.70)

Model 1, adjusted for No. of MetS components at 1st visit, age and sex; Model 2, Model 1 plus adjusted for smoking, drinking and exercise; Model 3, Model 2 plus adjusted for estimated GFR.

WC waist circumference, BP blood pressure, TG triglyceride, HDL-C high-density lipoprotein cholesterol; MetS, metabolic syndrome.