Table 1.

Novel genome-wide significant loci from multi-trait joint-analyses of neuropsychiatric disorders.

Disease	Locus	Chr	POS(hg19)	Lead SNP	Cytoband	Gene	A1	A2	Freq	Beta	SE	P
ADHD	1	3	49809841	rs9870755	3p21.31	IP6K1	T	C	0.16	0.090	0.016	6.14E−09
	2	5	92995013	rs71639293	5q15	FAM172A	A	G	0.81	0.090	0.016	2.53E−08
	3	11	49356806	rs10839264	11p11.12	FOLH1	T	C	0.08	0.118	0.021	2.27E−08
	4	18	39300226	rs8083506	18q12.3	PIK3C3,KC6	T	C	0.21	−0.089	0.015	6.19E−09
	5	20	44730245	rs6032660	20q13.12	NCOA5	A	G	0.74	−0.083	0.014	2.77E−09
BIP	6	1	95578207	rs12563424	1p21.3	TMEM56	T	C	0.64	−0.064	0.011	1.29E−08
MDD	7	1	191027948	rs10920885	1q31.2	RP11-309H21.3, LOC440704	T	G	0.81	−0.032	0.005	2.26E−09
	8	3	29756378	rs9834021	3p24.1	RBMS3	T	C	0.49	−0.023	0.004	3.18E−08
	9	7	114059156	rs2894699	7q31.1	AC073626.2, FOXP2	T	C	0.43	−0.025	0.004	4.15E−09
	10	11	28642653	rs4636654	11p14.1	RP11-960D24.1, METTL15	A	G	0.40	−0.027	0.004	2.83E−10
	11	11	66456387	rs2276138	11q13.2	SPTBN2	T	C	0.48	−0.023	0.004	2.18E−08
	12	13	97208898	rs1414622	13q32.1	HS6ST3	T	C	0.92	0.043	0.008	3.03E−08
	13	14	103301072	rs7146581	14q32.32	TRAF3	T	C	0.22	0.027	0.005	2.3E−08
	14	15	66529936	rs4776768	15q22.31	MEGF11	T	C	0.28	−0.025	0.005	3.71E−08
	15	18	39296488	rs8099746	18q12.3	PIK3C3,KC6	T	C	0.80	0.030	0.005	1.27E−08
	16	22	46457723	rs62228096	22q13.31	hsa-mir-4763, LOC150381	A	G	0.35	−0.026	0.004	4.84E−09

Disease the name of the neuropsychiatric disorders, ADHD attention deficit hyperactivity disorder, BIP bipolar disorder, MDD major depressive disorder, CHR chromosome, POS the position of each SNP on the human genome build hg19, SNP the most significantly associated SNP at each locus, Gene closest gene, A1 the effect allele, A2 the non-effect allele, Beta the association coefficient, Freq the frequency of the effect allele, SE the standard error of the effect size estimate; P P value in MTAG analysis.