Fig. 2.

The number of contact points between the DMTreC14 and cancer cell bilayers (left), and the normalized number of TreC14-related contact points (right). In the left, the total number of contact points, black; the number of contact points between TreC14 and the different lipid species (PC, PE, PS, or PI) in the cancer cell bilayer, red; and the number of contact points between DMPC and the above-mentioned lipid species, blue, are shown. In the right, the normalized number of TreC14-related contact points with respect to the total number of each lipid species in the cancer cell bilayer (PC, yellow; PE, cyan; PS, green; PI, orange) is shown. The normalized number of contact points with respect to the number of the PI lipids is sometimes larger than one because PI sometimes interacts with the trehalose moiety of the TreC14 lipid through multiple hydrogen bonds (or multiple electrostatic interactions). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)