Table 4.
Prognostic characteristics of tumor in breast cancer patients according to their breast volume (small vs. large).
| Variable | All patients n = 103 (100%) |
Small volume n = 57 (55.3%) |
Large volume n = 46 (44.6%) |
p |
|---|---|---|---|---|
| Clinical tumor size (mm) | 23.95 ± 16.46 | 23.07 ± 17.06 | 24.80 ± 16.02 | 0.65 |
| Tumor size pathological measurement (mm) | 23.80 ± 16.16 | 24.67 ± 18.53 | 22.70 ± 12.73 | 0.42 |
| Tumor size (examination) (cm) | ||||
| ≤ 2 cm | 58 (56.31%) | 35 (61.40%) | 23 (50.00%) | 0.19 |
| > 2 cm | 45 (43.68%) | 22 (38.60%) | 23 (50.00%) | |
| Clinical stage | ||||
| I | 30 (37.97%) | 18 (42.85% ) | 12 (32.43%) | 0.66 |
| II, III | 41 (51.90%) | 20 (47.61%) | 21 (56.75% ) | |
| III | 8 (10.13%) | 4 (9.52%) | 4 (10.81%) | |
| Pathological stage | ||||
| I | 36 (42.35% ) | 21 (44.68% ) | 15 (39.47%) | 0.96 |
| II, III | 40 (47.06% ) | 21 (44.68% ) | 19 (50%) | |
| IV | 9 (10.59% ) | 5 (10.64% ) | 4 (10.53%) | |
| Axillary involvement | ||||
| Negative | 48 (58.54%) | 26 (57.78%) | 22 (59.46%) | 0.87 |
| Positive | 34 (41.46%) | 19 (42.22%) | 15 (40.54%) | |
| Histological type | ||||
| Ductal | 92 (96.48%) | 51 (94.44%) | 41 (100%) | 0.17 |
| Lobulillar | 3 (3.16%) | 3 (5.56%) | 0 | |
| Differentiation grade | ||||
| 1, 2 | 53 (68.83% ) | 32 (74.42%) | 21 (61.76% ) | 0.48 |
| 3 | 24 (31.17% ) | 11 (25.58% ) | 13 (38.24% ) | |
| Lymphovascular invasion (n = 77)a | ||||
| Yes | 74 (96.10%) | 41 (97.62%) | 33 (94.29% ) | 0.72 |
| No | 3 (3.9%) | 1 (2.38%) | 2 (5.71% ) | |
| Ki-67 (n = 84)a | ||||
| (+) | 75 (89.29%) | 39 (86.67%) | 36 (92.31% ) | 0.52 |
| (−) | 9 (10.71%) | 6 (13.33%) | 3 (7.69% ) | |
| Ki-67 (%) (n = 84)a | 27.76 ± 22.3 | 27.96 ± 24.1 | 27.17 ± 20.3 | 0.93 |
| ER | ||||
| (+) | 76 (83.52%) | 37 (77.00%) | 39 (95.1%) | 0.04* |
| (−) | 15 (16.48%) | 11 (22.92%) | 2 (9.3%) | |
| PR | ||||
| (+) | 71 (78.02%) | 36 (75%) | 35 (81.4%) | 0.26 |
| (−) | 20 (21.98%) | 12 (25%) | 8 (18.6%) | |
| Cerb2 (a) | ||||
| (+) | 24 (28.24%) | 11 (24.44%) | 13 (32.5% ) | 0.40 |
| (−) | 61 (71.76%) | 34 (75.56%) | 27 (67.5%) | |
| NPI | 3.43 ± 1.78 | 3.34 ± 1.74 | 3.54 ± 1.84 | 0.62 |
| NPI | ||||
| < 2 | 14 (17.07%) | 8 (17.78%) | 6 (16.22% ) | 0.13 |
| 2–2.4 | 16 (19.52%) | 9 (20%) | 7 (18.92% ) | |
| 2.4–3.4 | 14 (17.07%) | 6 (13.33%) | 8 (21.62% ) | |
| 3.4–5.4 | 17 (20.73%) | 14 (31.11%) | 3 (8.11% ) | |
| > 5.4 | 21 (25.61%) | 8 (17.78%) | 13 (35.14% ) | |
Data expressed as means ± standard deviation and absolute numbers and their frequencies.
NPI Nottingham prognostic index.
*p value < 0.05 (t-Student or Chi-squared).
aAnalysis performed on the cases provided by the pathology department.