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. 2021 Jan 21;7:9. doi: 10.1038/s41531-020-00150-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Two representative traces showing spontaneous contractile response of colon preparations obtained from control (blue trace) and MPTP-treated (red trace) animals. b The frequency and c amplitude of spontaneous contraction in MPTP-treated (n = 6) and naïve (n = 7) animals; unpaired Student’s t-test. d The effect of carbachol on the change in tone of isolated distal colon in MPTP-treated (n = 6) and naïve (n = 8) animals); all values are mean ± SEM; Two-way repeated measure ANOVA.