Table 1.
The number of 5-HT-, TH- and substance P-ir cells in an area of 1 mm2 relation to the number of Huc/HuD-ir neurons. Each value is mean ± SEM. There were no significant differences between the number of HuC/HuD-ir cells or other markers in the proximal or distal colon in either control or tissues obtained from MPTP-treated animals.
| Number of immunoreactive neurones/mm2 | ||||||
|---|---|---|---|---|---|---|
| Markers/regions | Huc/HuD-ir | 5-HT-ir | Huc/HuD-ir | Tyrosine hydroxylase-ir | Huc/HuD-ir | Substance P-ir |
| Proximal colon - Control | 1445 ± 64.4, n = 7 | 302 ± 15.6, n = 7 | 1251 ± 44.6, n = 6 | 12 ± 6.4, n = 6 | 1495 ± 74.8, n = 5 | 479 ± 45.6, n = 5 |
| Proximal colon - MPTP | 1610 ± 102.4, n = 6 | 339 ± 24.6, n = 6 | 1416 ± 64.5, n = 6 | 12 ± 3.9, n = 6 | 1595 ± 75.8, n = 4 | 529 ± 99.3, n = 4 |
| Distal colon - Control | 1516 ± 59.5, n = 8 | 313 ± 13.0, n = 8 | 1580 ± 125.9, n = 8 | 9.5 ± 3.4, n = 8 | 1541 ± 37.5, n = 7 | 538 ± 45.1, n = 7 |
| Distal colon - MPTP | 1484 ± 68.1, n = 5 | 353 ± 22.8, n = 5 | 1546 ± 58.9, n = 6 | 8.4 ± 4.6, n = 6 | 1699 ± 95.4, n = 4 | 550 ± 24.8, n = 4 |