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. 2021 Jan 21;11:1862. doi: 10.1038/s41598-021-81249-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Results of the Weisskoff test: standard deviation over time of the mean resting signal as a function of the number of voxels averaged (see Eq. 1) at 1.5 T, 3 T and 7 T (a), (b) and (c), respectively. The voxels added were located in the middle of the cortex and the curves here correspond to TE = T2*_GM at each field. Each colour represents a subject, one line per hemisphere. The differences between the physiological noise levels are not significantly different (p = 0.49) between field strengths. (d) The average of the Weisskoff curves over subjects for the three fields studied. The circles correspond to the point in which the curve deviates from the plateau corresponding to the noise level where the physiological noise dominated regime has been reached (dashed lines with same colour-coding as for static field strength). The inset corresponds to the result for the first 300 voxels (without the circles).