Table 3.

Estimated olfactory bulb α-synuclein area fraction.

Cases	DxAP	Marker count	Total markers counted	Number of sections	Number of sampling sites	Grid spacing (µm)	Coefficient of error (Gundersen), m = 1	Counting frame area (XY) (µm²)	Sampling grid area (XY) (µm²)	Area fraction (%)
5	PD	465	2891	6	79	15	0.038	10,000	250,000	16.08
7	PD	1331	3007	4	78	15	0.035	10,000	1,000,000	44.26
8	PD	1163	2740	5	67	15	0.021	10,000	1,000,000	42.45
9	PD	996	2807	5	72	15	0.019	10,000	1,000,000	35.48
10	PD	727	2031	3	51	15	0.031	10,000	250,000	35.80
11	PD	1407	3430	4	86	15	0.035	10,000	1,000,000	41.02
12	PD	934	1926	7	51	15	0.025	10,000	1,000,000	48.49
14	PD	1258	3064	6	95	15	0.026	10,000	1,000,000	41.06
15	PD	1326	3707	5	92	15	0.040	10,000	1,000,000	35.77
16	PD	254	721	3	18	15	0.041	10,000	250,000	35.23
17	PD	424	1190	3	32	15	0.027	10,000	250,000	35.63