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. 2021 Jan 21;12:494. doi: 10.1038/s41467-020-20766-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a SEs are enriched in the key activation-induced genes. b The regulatory potential scores for TEs of the non-key activation-induced genes and SEs of the key activation-induced genes in resting (UN) or activated (ST) MCs were calculated either using H3K27ac ChIP-seq peaks (b) or using Omni-ATAC-seq peaks (c). d Average FPKM reads of RNA transcripts of the non-key activation-induced genes and key activation-induced genes in resting or activated mast cells (n = 3 biologically independent samples). Data a–c represent three biological samples. Middle line inside each box represents the median, upper and lower bounds of the box represent the third and first quartiles, respectively. Whiskers represent 1.5 times of the interquartile range. P-values were calculated by a two-tailed student’s t test without adjustments.