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. 2021 Jan 21;11:1932. doi: 10.1038/s41598-020-80563-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Global relevance of the inverse association of ADH1B expression with obesity traits. Meta-analysis, using a random effects model, was performed to evaluate the relationship between adipose ADH1B mRNA expression and BMI in populations from four ethnic groups (Europeans, African Americans, Pima Indians, and Mexican Americans) as indicated. The data show point estimates and 95% confidence intervals for BMI β-values in each ethnic group. Gray squares represent weighted contributions from each study, and the diamond represents the overall summary statistic. For each standard deviation of decreased ADH1B expression, BMI was increased by 0.56 standard deviations, *P < 0.001.