Manhattan plots showing the results of stepwise conditional analysis of the HLA region
(A) Unconditioned.
(B) Conditioning on rs2844678.
(C) Conditioning on rs2844678 + rs12524487.
(D) Conditioning on rs2844678 + rs12524487 + rs17193507.
(E) Conditioning on rs2844678 + rs12524487 + rs17193507 + rs12526858.
The −log10 p value for the genetic variants analyzed are plotted against their physical chromosomal position. The red line represents the genome-wide level of significance (p value < 5 × 10−8).