Figure 6.

Dot plot representing the cumulative genetic risk score (GRS) for Takayasu arteritis across the five major populations included in the 1000 Genomes Project

Each dot illustrates the GRS value of an individual, and the black lines represent the means and ranges. Data were used from the 1000 Genomes Project phase 3 release. African, n = 661; Admixed American, n = 347; East Asian, n = 504; European, n = 503; South Asian, n = 489. There was a significant difference between the GRSs among populations (ANOVA p value < 0.0001). The multiple comparison test on mean GRS between each pair of populations revealed statistically significant differences for all pairs (p value < 0.0001) except African versus East Asian and European versus South Asian (Tukey’s adjusted p value = 0.924 and 0.457, respectively).