Table 3.
Covariate and tertiles/groups | Male |
Female |
||||||
---|---|---|---|---|---|---|---|---|
Unadjusted analyses |
Adjusted analyses |
Unadjusted analyses |
Adjusted analyses |
|||||
OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |
Age | 0.97 (0.93–1.02) | 0.304 | NA | 1.03 (1.01–1.05) | 0.002 | 1.10 (0.99–1.04) | 0.091 | |
Disease duration | 1.11 (0.93–1.27) | 0.112 | NA | 1.02 (0.99–1.06) | 0.143 | NA | ||
Anti-CCP positivity | 1.05 (0.75–1.48) | 0.760 | NA | 1.12 (1.01–1.24) | 0.020 | 1.14 (1.01–1.27) | 0.023 | |
Current steroid dose | 0.94 (0.75–1.17) | 0.616 | NA | 1.01 (0.93–1.08) | 0.856 | NA | ||
DAS28 | 2.91 (1.48–5.7) | 0.002 | 2.87 (1.42–5.8) | 0.003 | 3.23 (2.49–4.19) | < 0.001 | 3.08 (2.31–4.1) | < 0.001 |
BMI | 1.01 (0.88–1.16) | 0.846 | NA | 1.07 (1.01–1.06) | 0.014 | a | ||
Skeletal muscle mass | 1.00 (0.91–1.11) | 0.944 | NA | 0.98 (0.91–1.06) | 0.699 | NA | ||
Body fat mass | 1.00 (0.92–1.08) | 0.947 | NA | 1.03 (1.0–1.06) | 0.023 | 0.99 (0.95–1.03) | 0.740 | |
Body fat/skeletal muscle ratio | 1.53 (0.61–3.8) | 0.355 | NA | 2.01 (1.04–3.85) | 0.037 | 1.82 (0.85–3.88) | 0.120 | |
HAQ | 9.51 (1.25–71.94) | 0.029 | 7.97 (0.85–74.62) | 0.069 | 3.99 (2.4–6.65) | < 0.001 | 1.22 (0.68–2.18) | 0.503 |
OR, odds ratio; CI, confidence interval; NA, not applicable; CCP, citrullinated protein antibody; DAS28, disease activity score in 28 joints; BMI, body mass index; HAQ, health assessment questionnaire.
BMI was excluded from multivariable analysis due to collinearity problems with fat mass.