Table 4.
Univariable and multivariable Cox regression analyses to evaluate the probability for prolonged negative conversion in mild coronavirus disease 2019 patients
| Variable | Univariable analysis | p value | Multivariable analysis | p value | ||
|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | |||
| Age ≥ 65 yr | 7.97 | 1.08–5.91 | 0.042 | 4.21 | 0.47–38.05 | 0.200 |
| Female sex | 1.10 | 0.60–2.02 | 0.755 | - | - | - |
| Body mass index ≥ 25 kg/m2 | 1.09 | 0.33–3.55 | 0.887 | 1.54 | 0.44–5.38 | 0.498 |
| Current smoker | 1.35 | 0.53–3.45 | 0.535 | - | - | - |
| Household contact | 9.49 | 1.27–70.82 | 0.028 | 4.34 | 0.55–34.48 | 0.165 |
| Hypertension | 2.28 | 0.88–5.87 | 0.088 | 1.23 | 0.36–4.19 | 0.738 |
| Diabetes mellitus | 1.44 | 0.44–4.69 | 0.550 | - | - | - |
| Cardiopulmonary disease | 3.80 | 0.52–28.07 | 0.190 | - | - | - |
| Abnormality in sense of smell and taste | 0.28 | 0.14–0.57 | < 0.001 | 0.32 | 0.15–0.68 | 0.003 |
| Myalgia | 1.09 | 0.58–2.06 | 0.782 | - | - | - |
| Sore throat | 1.29 | 0.70–2.36 | 0.418 | - | - | - |
| Cough | 1.66 | 0.90–3.06 | 0.102 | - | - | - |
| Sputum | 2.73 | 1.37–5.47 | 0.004 | 1.86 | 0.88–3.92 | 0.102 |
| Chest discomfort | 1.60 | 0.49–5.19 | 0.433 | - | - | - |
| Dyspnea | 4.23 | 0.58–31.07 | 0.157 | - | - | - |
| Fever | 1.37 | 0.72–2.62 | 0.340 | - | - | - |
| Rhinorrhea or nasal obstruction | 0.74 | 0.39–1.38 | 0.340 | - | - | - |
| Diarrhea | 2.07 | 0.91–4.70 | 0.082 | 0.93 | 0.34–2.53 | 0.881 |
| No symptoms | 0.24 | 0.03–1.79 | 0.166 | - | - | - |
| Pneumonia development during hospitalization | 2.73 | 1.20–6.21 | 0.016 | 2.90 | 1.06–7.97 | 0.039 |
HR, hazard ratio; CI, confidence interval.