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. 2019 Dec 20;36(1):67–75. doi: 10.3904/kjim.2018.290

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Copyright © 2021 The Korean Association of Internal Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Effects of the pretreatment with glibenclamide on gastroprotection of irsogladine maleate (IM) in mice subjected to ethanol/hydrochloric acid (HCl)-induced gastric damage. Glibenclamide (10 mg/kg, intraperitoneal) or vehicle was injected 30 minutes before the administration of IM (1 mg/kg, orally) or water to each group. Sixty minutes after, gastric mucosal lesions were induced with ethanol/HCl (20 mL, orally) in all groups. Each value represents the mean ± SD of the percentage of ulcerated gastric area (n = 5/group).