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. 2020 Dec 21;108(1):100–114. doi: 10.1016/j.ajhg.2020.12.001

Figure 1.

Figure 1

De novo mutations are enriched in brain genes and in OMIM disease genes

Enrichment of DNMs ±2 SE by variant class for all genes, gene expressed in the brain, genes that are disease causing in OMIM, and the intersection of brain-expressed genes and OMIM disease genes (Brain Disease Genes).