Figure 6.

CREST performance on the Generation Scotland data

(A and B) The sensitivity (A) and specificity (B) of relationship type classification for GP, AV, and HS pairs, and the average across these three types in the GS dataset. These plots use a genome coverage rate (C) bin size of 0.05 because several bins have a small number of HS and GP pairs with a bin size of 0.025 (minimum of 7 for HS and 7 for GP using 0.025 versus 14 and 16 here).

(C) Histograms showing the distributions of LOD scores for the inferred parental sex of HS (top) and GP (bottom) pairs. Blue samples represent scores for pairs where the reported sex is male, and likewise red for female.