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. 2021 Jan 8;8:575029. doi: 10.3389/fpubh.2020.575029

Figure 3.

Figure 3

(A) An “alternative” pathophysiological hypothesis for Covid-19 pandemia developed at the department of internal medicine. Amusing moments helped staff to face the disaster (modified from https://www.news-medical.net/health/Blood-Plasma-Components-and-Function-(Italian).aspx). (B) (a) Some Covid-19 patients had myoclonus with a typical electroencephalographic (EEG) pattern showing both periodic lateralized epileptiform discharges (PLEDs) and bilateral PLEDs (bi-PLEDs), predominantly involving the left hemisphere, mainly recorded in the parasagittal and midline regions. (b,c) Black arrows indicate myoclonic jerks, without any correlation with periodic lateralized discharges, nor with a prominent proximal-to-distal gradient of appearance (surface electromyography recorded from the right sternocleidomastoid, extensor carpi radialis longus, and tibialis anterior muscles). (C) The virus as seen by an autistic child aged 8. In children with psychiatric disorders, Covid-19 remarkably influenced their thought and mood. (D) The algorithm for ventilation used in our patients (PEEP, positive end-expiratory pressure; SpO2, pulse oximetry; FiO2, fractional inspiration of oxygen; NiV, non-invasive ventilation; CPAP, continuous positive airway pressure).