Skip to main content
. 2020 Jun 2;117(2):367–385. doi: 10.1093/cvr/cvaa155

Table 3.

Recommendations

1 Correct nomenclature should be always used when describing sex- or gender-related differences in IHD.
2 Experimental studies investigating IHD should include subjects from both sexes and, if not possible, results should be cautiously interpreted.
3 For any observed sexual dimorphic phenotype in IHD, it should be determined whether it is dependent on the hormonal state and if it is specific to or modified by genetic sex.
4 All relevant experimental details including age, strain, and sex should be clearly provided, preferably also in the searchable parts of the MS, for example, abstract and title.
5 Combination of IHD and comorbidities in preclinical models in male and female animals should be encouraged.
6 Peer-review of studies investigating IHD and comorbidities should always consider whether potential sex-specific effects have been accounted for.
7 Educational programmes in Cardiology and basic cardiovascular research should include elements addressing sex differences in Biology and Medicine.
8 Research should include a wide spectrum of diseases present in an adult population of both sexes and consider the sex-related effects of comedications.
9 Scientific Societies and Funding agencies should provide financing through dedicated calls or consider rewards/bonuses/incentives covering higher costs and longer duration of research in this area.