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. 2021 Jan 8;10:607593. doi: 10.3389/fonc.2020.607593

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Copyright © 2021 Lu, Li, Zhang, Luo, Chen, Ma, Chen, Wang, Pu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GFI1 acted as a transcription inducer of LINC00675. (A) DNA motif of GFI1 in the promoter of LINC00675. (B, C) Expression of GFI1 in QGY-7703 and SMCC-7721 cells transfected with siRNA of GFI1 for 48 h. (D) The predicted three binding sites of GFI1 in LINC00675 promoter. (E, F) Luciferase activity analysis of the binding sites in HCC cells transfected with GFI1 oligonucleotides. *P < 0.05.