Table 3.
Comparisons of ADC histogram parameters according to TILs and the ER/PR/HER2 status.
| Luminal (n=72) | Non-luminal (n=42) | Luminal (n=72) | Non-luminal (n=42) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| TIL levels | P-value | Low level (n=50) |
High level (n=22) |
P-value | Low level (n=16) |
High level (n=26) |
P-value | ||
| 10th percentile ADC (×10−6 mm2/s) | 775.07 ± 191.47 | 898.67 ± 136.79 | <0.001 | 744.12 ± 188.17 | 845.41 ± 175.22 | 0.041 | 910.19 ± 128.14 | 891.58 ± 143.87 | 0.674 |
| 25th percentile ADC (×10−6 mm2/s) | 908.89 ± 189.57 | 1,019.31 ± 158.68 | 0.002 | 880.30 ± 176.09 | 973.86 ± 198.58 | 0.118 | 1,030.38 ± 143.13 | 1,012.50 ± 169.93 | 0.728 |
| 50th percentile ADC (×10−6 mm2/s) | 1,078.58 ± 222.23 | 1,172.21 ± 195.06 | 0.025 | 1,048.08 ± 184.25 | 1,147.91 ± 274.43 | 0.196 | 1,185.63 ± 179.54 | 1,163.96 ± 207.06 | 0.731 |
| 75th percentile ADC (×10−6 mm2/s) | 1,281.60 ± 281.84 | 1,369.62 ± 269.74 | 0.092 | 1,249.76 ± 221.87 | 1,353.96 ± 370.06 | 0.326 | 1,387.25 ± 204.00 | 1,358.89 ± 261.45 | 0.714 |
| 90th percentile ADC (×10−6 mm2/s) | 1,489.97 ± 328.38 | 1,589.62 ± 269.74 | 0.099 | 1,460.20 ± 295.27 | 1,557.64 ± 378.51 | 0.361 | 1,599.94 ± 212.35 | 1,583.27 ± 303.58 | 0.849 |
| skewness | 0.46 ± 0.62 | 0.63 ± 0.62 | 0.152 | 0.41 ± 0.0.64 | 0.56 ± 0.54 | 0.197 | 0.58 ± 0.41 | 0.66 ± 0.72 | 0.671 |
| entropy | 1.42 ± 1.67 | 1.55 ± 1.79 | 0.705 | 6.49 ± 1.33 | 6.54 ± 1.34 | 0.120 | 7.47 ± 1.46 | 7.09 ± 1.35 | 0.396 |
| kurtosis | 6.51 ± 1.34 | 7.23 ± 1.39 | 0.007 | 1.33 ± 1.64 | 1.62 ± 1.69 | 0.903 | 0.86 ± 1.00 | 1.97 ± 2.04 | 0.023 |