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. 2020 Oct 27;43(2):601–612. doi: 10.1002/hed.26515

TABLE 3.

Staging changes from TNM7 to TNM8 for p16‐negative HNSCC patients a

TNM7 TNM8 Staging variation
Stage No. of patients Stage No. of patients Staging variation
III 337 III 337 No change
IVa 722 III 8 1% downstaging
IVb 594 82% no change
IVb
  • 54 oral cavity

  • 27 p16‐neg oropharynx

  • 26 hypopharynx

  • 13 larynx

120 17% upstaging
IVb 101 IVb 1 <1% downstaging
IVb 100 >99% no change
a

All tumor sites.