FIGURE 4.

Reduced postsynaptic density (PSD) length in idiopathic intracranial hypertension (IIH) compared to reference (REF). (a,b) EM showing PSD in a REF subject, revealing the pre‐ (Pre) and postsynaptic (Post) terminals. (c) PSD in an individual with IIH, revealed as length of PSD. (d) The PSD length was nearly twofold higher in REF than IIH patients (0.61 ± 0.09 vs. 0.34 ± 0.05 µm (p < 0.001; independent samples t test, t = 5.391, df = 11). Error bars are 95% CI. Magnification 43,000×; scale bar 500 nm