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. 2020 Oct 12;69(3):655–680. doi: 10.1002/glia.23919

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© 2020 The Authors. GLIA published by Wiley Periodicals LLC

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Intranasally administered silica coated gold nanoparticle‐labeled MSCs evenly distribute throughout the brain after dWMI induction. (a,b) After intranasal administration of nanoparticle‐labeled MSCs at D3 (i.e., P8) after injury induction or sham operation, the highest mass of gold was observed in the brain for dWMI animals (n=6) (a) versus peripheral organs in sham‐control animals (n=6) (b). (c) Gold nanoparticles, used to label MSCs, were evenly distributed throughout the brain parts after dWMI **p < .01; ***p < .001 peripheral organs versus brain