Table III.

Input Values for Exposure Estimation and DALYs Calculation of Chemicals

Parameter	Value	Unit	Explanation
BW_m; BW_f	Male:85; Female:74	kg	Body weight of Dutch people. The average value calculated from the source 1
Cons_milk	258	g/day	Dutch milk consumption. 7–68 years old 1
Tf	0.5	years	The average value 2
Dwf	0.508		Terminal phase with medication; reference from FERG 3
Pf	92	%	The average value 2
t_nf	5	years	The average value 2
Dwnf	0.294		Diagnosis and primary therapy; reference from FERG
LE_m; LE_f	75.2; 80.5	Years	The life expectancy for Dutch male and female. Average value 4
Age_HCC	60	years	Refence age 5
Sex_dist_f/m	50:50	%	An equal age distribution was assumed 6
Rfa‐	0.01	cases	Cases/100,000/year/ng/kg bw/day aflatoxin exposure for individuals without HBV infection 7
Rfa+	0.3	cases	Corresponding cases for individuals with HBV infection 7
Phbv	0.5	%	Worst case were assumed 8
RR_AFM1_AFB1	10	%	Reference value 9
EXP_DF	1.3	pg of TEQ/kg bw per day	Reference value 10
IRi (IR_Hpre, IR_Hpos, IR_Infer)	0.010968, 1.29498, 0.0109686		Diseases incidences rate caused by exposure estimation of dioxins for: infertility; hypothyroidy due to prenatal exposure; hypothyroidy due to postnatal exposure. Reference value 3
DWi (DW_Hpre, DW_Hpos, DW_Infer)	0.019, 0.019, 03056		Disability weight of diseases caused by dioxins for: infertility; hypothyroidy due to prenatal exposure; hypothyroidy due to postnatal exposure. Reference value 3
DRDi (DRD_Hpre, DRD_Hpos, DRD_Infer)	80, 60, 25	Years	Duration until remission or death for: Infertility; hypothyroidy due to prenatal exposure; hypothyroidy due to postnatal exposure. Reference value 3

¹Van Rossum et al. (2011).

²Assunção et al. (2018).

³Devleesschauwer et al. (2015).

⁴Van Kreijl et al. (2006).

⁵Verhoef et al. (2004).

⁶WHO (2015b).

⁷Liu & Wu (2010).

⁸Koopsen et al. (2019).

⁹Wu, Narrod, Tiongco, and Liu (2011).

¹⁰Boon et al. (2014).