TABLE 2.
Patient data and sample 1—GOSE
| Unfavourable GOSE 1–4 (n = 17) | Favourable GOSE 5–8 (n = 39) | p | |
|---|---|---|---|
| Sex (female) | 14 (82) | 28 (72) | 0.51 |
| Age (years) | 58 (54–64) | 56 (48–64) | 0.28 |
| GCS | 11 (7–13) | 14 (13–15) | 0.01 |
| Modified Fischer Grade 0–2 | 0 (0) | 4 (10) | 0.02 |
| Modified Fischer Grade 3–4 | 17 (100) | 35 (90) | 0.02 |
| IL‐1Ra | 369 (187–524) | 155 (87–253) | 0.007 |
| IL‐6 | 3.30 (0.45–6.93) | 0.45 (0.06–2.92) | 0.01 |
| TNF–α | 23.2 (18.2–29.5) | 18.2 (15.1–20.9) | 0.02 |
| ICAM−1 | 178082 (144650–235454) | 138668 (87755–190669) | 0.05 |
| CRP | 49 (15–73) | 7 (3–20) | 0.01 |
| WCC (1/0) a | 12.7 (10.4–16.0) | 11.2 (8.9–14.1) | 0.23 |
| Platelets (1/0) a | 220 (180–252) | 251 (199–297) | 0.09 |
| Temperature (1/0) a | 38.2 (37.6–38.7) | 37.9 (37.4–38.2) | 0.14 |
Number (per cent) or median with interquartile ranges. IL‐1Ra, IL‐6, TNF‐α, ICAM‐1 concentrations in picogram/L, CRP in mg/L, WCC and platelets count 109/L, temperature in degrees Celsius.
Two patients were lost to follow‐up, making the total patients with scored GOSE n = 56.
Abbreviations: CRP, C‐reactive protein; ICAM, intracellular adhesion molecule; IL‐1Ra, interleukin‐1 receptor antagonist; IL‐6, interleukin 6, TNF‐α, tumour necrosis factor alpha; WCC, white cell count.
a
Number of missing in the two groups, respectively.