Fig. 2.

Experimental design for evaluating repeatability of CNNs for (a) slice-level classification of clinically significant prostate cancer (csPCa: Gleason grade group (GGG) > 1) and non-csPCa regions and (b) lesion-level detection and segmentation of csPCa regions. N = 112 patients scheduled for prostatectomy underwent two prostate MR examinations (S_A and S_B) performed on the same day approximately 15 min apart. The scans, S_A and S_B, were divided into training set (A_train and B_train), N = 78, and test set (A_test and B_test) N = 34. Two different instances N_A and N_B were trained on scans A_train and B_train, respectively, and evaluated on a combined test set, S_test (A_test + B_test). The outputs P₁ and P₂ by N_A and N_B, respectively, on S_test are used to calculate repeatability of the CNNs