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. 2021 Jan 22;20:24. doi: 10.1186/s12933-021-01216-7

Table 2.

Unadjusted and multivariable-adjusted HRs for incidence of AF comparing people with and without diabetes by sex, and hazard ratio for women relative to men

Number Person-time Number of patients with AF during FU Incidence rate (95% CI) Hazard ratio (95% CI) Women-to-men ratio (95% CI)
Diabetes vs no diabetes (HR in women/HR in men)
Unadjusted Adjusted Unadjusted Adjusted
Women
 No diabetes 1,416,545 6,855,046.80 114 855 1.68 (1.67–1.69)
 Type 1 diabetes 21,440 97,121.95 2 557 2.63 (2.53–2.74) 1.50 (1.44–1.56) 1.32 (1.27–1.37)
 Type 2 diabetes 158,536 697,591.24 23,556 3.38 (3.33–3.42) 1.93 (1.90–1.96) 1.17 (1.16–1.19)
1.35 (1.28–1.42) 1.18 (1.12–1.24) for type 1 diabetes
1.20 (1.18–1.22) 1.10 (1.08–1.12) for type 2 diabetes
Men
 No diabetes 1,113 974 4 971 106.10 145 269 2.92 (2.91–2.94)
 Type 1 diabetes 23,949 103,232.26 3 474 3.37 (3.26–3.48) 1.12 (1.09–1.16) 1.12 (1.08–1.16)
 Type 2 diabetes 186,963 751,998.44 37,301 4.96 (4.91–5.01) 1.64 (1.62–1.65) 1.10 (1.09–1.12)

Adjusted for age at inclusion and baseline characteristics (among smoking, obesity, hypertension, hypercholesterolemia, alcohol abuse, previous stroke, and non-cardiovascular comorbidities). Women to men ratio > 1 indicates an excess risk for incident AF in women with prevalent type 1 or type 2 diabetes mellitus compared with men with prevalent similar type of diabetes mellitus

HR hazard ratio, WMR women-to-men ratios